Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC729H1141N211O200S5

DescriptionStandard

        MPKVQFKERTATDYLVVHCAATKASMDIGVREIRQWHVQKGWLDIGYHFVIRRNGTVEDGRPHNVIGAHVEGFNARSLGICLAGGIDDKGNPQNNFTPEQFASLKLLLLAQKRTYPNAKIVGHHDLFAGKACPSFKVADWLKSVGI
    

Molecular Weight16221.48 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)6.09

Net Charge (pH 7.4) 5.44

Charge Density (pH 7.0) 0.0417

GRAVY Index-0.24

Hydrophobic Moment 0.68

Boman Index0.03

Instability Index28.49

Aliphatic Index 86.16

Aromaticity 0.0890

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6587.92

LogP -60.99

H-bond Donors 229.0

H-bond Acceptors 218.0

Rotatable Bonds 536.0

Heavy Atoms 1145.0

Ring Count 29.0

Amide Bonds 158.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0185054 VERIFIED: NO

Provenance & Taxonomy

OrganismPseudomonas phage shl2 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic