Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC552H897N153O168S2

DescriptionStandard

        PDLSGYEKSGLGNVNYNISRIRITAVEFPSASISLIPRAGIKLVIGNASLTIDTNWNIRTWMFKDSGRITVYISKVFVTAIFSTPLDSRGRTSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12429.08 Da

Isoelectric Point (pI)9.92

Net Charge (pH 7.0)5.95

Net Charge (pH 7.4) 5.86

Charge Density (pH 7.0) 0.0522

GRAVY Index-0.00

Hydrophobic Moment 0.58

Boman Index0.06

Instability Index14.44

Aliphatic Index 98.33

Aromaticity 0.0789

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5201.09

LogP -59.50

H-bond Donors 190.0

H-bond Acceptors 176.0

Rotatable Bonds 413.0

Heavy Atoms 875.0

Ring Count 15.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0108999 VERIFIED: NO

Provenance & Taxonomy

OrganismAlectura lathami [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria