Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC448H709N113O142S13

DescriptionStandard

        MKSFSVAVAVVIVFTLICLQESSAVPVTEVPELEGDISSDDAAASYEETSVETWMMPFDIRQKPQSGLIRCSYCCDCCALGVCGMCCKRGLLYEH
    

Molecular Weight10366.94 Da

Isoelectric Point (pI)4.38

Net Charge (pH 7.0)-7.48

Net Charge (pH 7.4) -7.90

Charge Density (pH 7.0) -0.0787

GRAVY Index0.36

Hydrophobic Moment 0.42

Boman Index0.16

Instability Index53.68

Aliphatic Index 87.16

Aromaticity 0.0737

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4029.87

LogP -39.24

H-bond Donors 148.0

H-bond Acceptors 149.0

Rotatable Bonds 337.0

Heavy Atoms 716.0

Ring Count 13.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0174443 VERIFIED: NO

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal