Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC355H561N95O97S10

DescriptionStandard

        MKIVYYLLHFLCYMTFILQATCSLIDAERCTKRYGNCRRNCYKREKQIDICFSVRKICCLEIFEDD
    

Molecular Weight8032.48 Da

Isoelectric Point (pI)8.45

Net Charge (pH 7.0)2.52

Net Charge (pH 7.4) 2.11

Charge Density (pH 7.0) 0.0381

GRAVY Index-0.02

Hydrophobic Moment 0.66

Boman Index-0.06

Instability Index54.21

Aliphatic Index 88.64

Aromaticity 0.1364

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3158.06

LogP -22.89

H-bond Donors 121.0

H-bond Acceptors 111.0

Rotatable Bonds 272.0

Heavy Atoms 557.0

Ring Count 10.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418910 VERIFIED: NO

Provenance & Taxonomy

OrganismMarmota marmota marmota [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence