Peptide Database

Peptide NameEfalizumab

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length125 amino acids

Chemical FormulaC634H956N166O186S5

DescriptionStandard

        EVQLVESGGGLVQPGGSLRLSCAASGYSFTGHWMNWVRQAPGKGLEWVGIMIHPSDSETRYNQKFKDIRFTISVDKSKNTLYLQMNSLRAEDTAVYYCARIGIYFYGTTYFDYIWGQGTLVTVSS
    

Molecular Weight14039.70 Da

Isoelectric Point (pI)8.03

Net Charge (pH 7.0)0.99

Net Charge (pH 7.4) 0.66

Charge Density (pH 7.0) 0.0080

GRAVY Index-0.20

Hydrophobic Moment 0.50

Boman Index0.09

Instability Index23.58

Aliphatic Index 75.60

Aromaticity 0.1440

Extinction Coeff. Reduced 35410.00

Extinction Coeff. Oxidized 35535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5678.17

LogP -55.32

H-bond Donors 204.0

H-bond Acceptors 194.0

Rotatable Bonds 454.0

Heavy Atoms 991.0

Ring Count 27.0

Amide Bonds 134.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0319507 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Cricetulus griseus [Animal]

FamilyMonoclonal antibody

Tax ID9606;10029

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Immunomodulatory

Half-Life5 days