Peptide Database

Peptide NameThyrotropin-releasing hormone

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length3 amino acids

Chemical FormulaC16H23N5O6

DescriptionStandard

EHP

Molecular Weight381.38 Da

Isoelectric Point (pI)5.24

Net Charge (pH 7.0)-1.08

Net Charge (pH 7.4) -1.30

Charge Density (pH 7.0) -0.3587

GRAVY Index-2.77

Hydrophobic Moment 0.30

Boman Index-0.34

Instability Index-28.07

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 178.71

LogP -1.30

H-bond Donors 5.0

H-bond Acceptors 6.0

Rotatable Bonds 9.0

Heavy Atoms 27.0

Ring Count 2.0

Amide Bonds 2.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0383256 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyTRH

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Hormone Neuropeptide