Peptide Database

Peptide NameOmalizumab

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length447 amino acids

Chemical FormulaC2187H3362N582O668S14

DescriptionStandard

        EVQLVESGGGLVQPGGSLRLSCAVSGYSITSGYSWNWIRQAPGKGLEWVASITYDGSTNYADSVKGRFTISRDDSKNTFYLQMNSLRAEDTAVYYCARGSHYFGHWHFAVWGQGTLVTVSSGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKAEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    

Molecular Weight48944.50 Da

Isoelectric Point (pI)8.21

Net Charge (pH 7.0)3.80

Net Charge (pH 7.4) 2.74

Charge Density (pH 7.0) 0.0085

GRAVY Index-0.38

Hydrophobic Moment 0.48

Boman Index0.03

Instability Index44.89

Aliphatic Index 70.76

Aromaticity 0.0984

Extinction Coeff. Reduced 84800.00

Extinction Coeff. Oxidized 85425.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161594 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Chinese hamster ovary cell line [Animal]

FamilyMonoclonal antibody

Tax ID9606; 10029

Structure & Mods

Configsingle-chain therapeutic peptide/protein [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory

Half-Life624 hours