Peptide Database

Peptide NameSLAY-screened peptide P1327

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC118H172N32O29

DescriptionStandard

        ATYLWTHNYHLIVYPTTRPR
    

Molecular Weight2502.83 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)1.97

Net Charge (pH 7.4) 1.67

Charge Density (pH 7.0) 0.0984

GRAVY Index-0.58

Hydrophobic Moment 0.31

Boman Index0.01

Instability Index35.85

Aliphatic Index 78.00

Aromaticity 0.2000

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 980.29

LogP -6.14

H-bond Donors 36.0

H-bond Acceptors 33.0

Rotatable Bonds 70.0

Heavy Atoms 179.0

Ring Count 9.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0059149 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/