Peptide Database

Peptide NameBeta-defensin 5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC310H511N83O80S9

DescriptionStandard

        MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK
    

Molecular Weight6969.47 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)6.51

Net Charge (pH 7.4) 6.13

Charge Density (pH 7.0) 0.1017

GRAVY Index0.69

Hydrophobic Moment 0.63

Boman Index0.23

Instability Index54.73

Aliphatic Index 112.66

Aromaticity 0.0781

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2602.23

LogP -22.76

H-bond Donors 97.0

H-bond Acceptors 97.0

Rotatable Bonds 232.0

Heavy Atoms 482.0

Ring Count 8.0

Amide Bonds 69.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0191281 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0371905 VERIFIED: YES