Peptide Database

Peptide NameDermaseptin-S7

Function Ontology

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Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC122H215N33O27S

DescriptionStandard

        LWKNMLKGIGKLAGKAALGAVKKLV
    

Molecular Weight2608.28 Da

Isoelectric Point (pI)10.70

Net Charge (pH 7.0)5.75

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.2302

GRAVY Index0.46

Hydrophobic Moment 0.70

Boman Index0.20

Instability Index-9.25

Aliphatic Index 132.80

Aromaticity 0.0400

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 976.72

LogP -4.65

H-bond Donors 34.0

H-bond Acceptors 34.0

Rotatable Bonds 94.0

Heavy Atoms 183.0

Ring Count 2.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224905 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)