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MYP_009149
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Basic Information
Act Beta-defensin 2 (18-40)[C12I,C-del] linear
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
22 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
RXPGRTRQIGTIFGPRIKXRSW
Physicochemical Analysis
0.00 Da
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0061444 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2,19
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa NCTC 6751[LC = 5 microM]
PMID25791057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25791057/
RECORD: Rec_0120780 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2,19
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa NCTC 6751[LC = 13 microM]
PMID25791057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25791057/
RECORD: Rec_0142547 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2,19
Bio-Activity Profile
Hemolytic
Human erythrocytes (70% Hemolysis at 3 microM, Human erythrocytes (20% Hemolysis at 3 microM
3 μM
Hemolysis
PMID25791057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25791057/
RECORD: Rec_0220196 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2,19
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli MG1655[LC = 4 microM]
PMID25791057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25791057/
RECORD: Rec_0229435 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2,19
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 8530[LC = 5 microM]
PMID25791057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25791057/
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