Peptide Database

Peptide NameFungal defensin oryzeasin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC311H506N92O95S7

DescriptionStandard

        MKLLTVAFSLLLLGQVHASPLVLDKRSSCQLGDVWDLNAADAACSASCAIQHGDKHGGHCDKNKVCVCN
    

Molecular Weight7278.36 Da

Isoelectric Point (pI)6.87

Net Charge (pH 7.0)-0.21

Net Charge (pH 7.4) -0.73

Charge Density (pH 7.0) -0.0030

GRAVY Index0.19

Hydrophobic Moment 0.52

Boman Index0.11

Instability Index40.27

Aliphatic Index 98.99

Aromaticity 0.0290

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2979.79

LogP -33.69

H-bond Donors 107.0

H-bond Acceptors 106.0

Rotatable Bonds 243.0

Heavy Atoms 505.0

Ring Count 8.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0270169 VERIFIED: YES

Provenance & Taxonomy

OrganismAspergillus oryzae [Fungus]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria