Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length523 amino acids

Chemical FormulaC2611H4079N647O748S29

DescriptionStandard

        MLHFVIVALMLLPHTCGQNPAIQVLLTNKGLQYGKHVGAEWIQDMLDHVTLPDIQGTFSTLFGPVSYTLSGITITKCDFPEPNVEYSQEYSGFKTSITDLSVALSGNWATKFGILHESGSFDMAIFGVDVTSVVKLEGKADGHLSVSSIICDGEVQDVDIRLYGGFSWIFQPFVHYMKGHIIEEIRKNICPAVQTSIEELESHLQAMNVSFDVNQVLSLELPLSGSPVVSPSNLTLGLKGEFYSIQTHAEPPFKSKPFMMPNIPGYMLSAGVSEFTLNSAAYGYFSAGKLQILITEKMVPKFSPIHLNTSSMGPYIPQLPKLFPGLPMTLQVYATEAPTFSLQSDIVNLTVRAAVKASAVESNGSSIPLFGVNVVVMLSGKMWIADGKVKGSVMLNNFTLTLASTQVGPFKTDSLENMCKKGIELFGVPQVNKKLAEGVMLPRMKRIQPVNSILTVEKVSIYQSSSFCKFLFFFSNHTLFLENRDLLPFLQMLKCWTCCEASSVVTSSKHKGLKSKSSLCFDF
    

Molecular Weight57431.09 Da

Isoelectric Point (pI)6.50

Net Charge (pH 7.0)-2.42

Net Charge (pH 7.4) -3.56

Charge Density (pH 7.0) -0.0046

GRAVY Index0.18

Hydrophobic Moment 0.60

Boman Index0.19

Instability Index41.56

Aliphatic Index 93.86

Aromaticity 0.0975

Extinction Coeff. Reduced 46870.00

Extinction Coeff. Oxidized 47495.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0219293 VERIFIED: NO

Provenance & Taxonomy

OrganismOryzias sinensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence