Peptide Database

Peptide NameSLAY-screened peptide P2790

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC77H132N26O22S2

DescriptionStandard

        TVRTPTNCVHRLACPAV
    

Molecular Weight1838.16 Da

Isoelectric Point (pI)9.00

Net Charge (pH 7.0)1.47

Net Charge (pH 7.4) 1.20

Charge Density (pH 7.0) 0.0862

GRAVY Index0.24

Hydrophobic Moment 0.70

Boman Index-0.00

Instability Index42.95

Aliphatic Index 85.88

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 767.60

LogP -9.41

H-bond Donors 29.0

H-bond Acceptors 27.0

Rotatable Bonds 53.0

Heavy Atoms 127.0

Ring Count 3.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0235117 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/