Peptide Database

Peptide NameFMRFamide-like neuropeptide AF7

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC46H70N14O9

DescriptionStandard

        AGPRFIRF
    

Molecular Weight963.14 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)1.80

Net Charge (pH 7.4) 1.61

Charge Density (pH 7.0) 0.2245

GRAVY Index0.11

Hydrophobic Moment 0.78

Boman Index-0.01

Instability Index-0.68

Aliphatic Index 61.25

Aromaticity 0.2500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 382.03

LogP -1.99

H-bond Donors 14.0

H-bond Acceptors 11.0

Rotatable Bonds 28.0

Heavy Atoms 69.0

Ring Count 3.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084463 VERIFIED: YES

Provenance & Taxonomy

OrganismAscaris suum [Animal]

FamilyFMRFamide related peptide

Tax ID6253

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0224702 VERIFIED: YES

Provenance & Taxonomy

OrganismAscaris suum [Animal]

FamilyFMRFamide-like neuropeptide AF7

Tax ID6253

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0328037 VERIFIED: NO

Provenance & Taxonomy

OrganismAscaris suum,Ascaris lumbricoides [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0385443 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyFMRFamide-like peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/