Peptide Database

Peptide NameBeta-defensin 25

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length49 amino acids

Chemical FormulaC241H370N72O70S7

DescriptionStandard

        EFKRCWNGQGACRTFCTRQETFMHLCPDASLCCLSYSFKPSRPSRVGDV
    

Molecular Weight5620.41 Da

Isoelectric Point (pI)8.68

Net Charge (pH 7.0)2.87

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.0585

GRAVY Index-0.42

Hydrophobic Moment 0.42

Boman Index-0.13

Instability Index75.78

Aliphatic Index 39.80

Aromaticity 0.1224

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2300.30

LogP -26.72

H-bond Donors 88.0

H-bond Acceptors 81.0

Rotatable Bonds 179.0

Heavy Atoms 390.0

Ring Count 11.0

Amide Bonds 51.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0004006 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

RECORD: Rec_0065077 VERIFIED: YES