MYP_008978
Basic Information
Dermaseptin-BI (Dermaseptin B1; Frogs, amphibians, animals)
Anticancer
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Antiparasitic Antiprotozoal
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytolysis / cell lysis Cytolytic activity
Standard
31 amino acids
C142H239N39O40S
Standard
Sequence
AMWKDVLKKIGTVALHAGKAALGAVADTISQ
Physicochemical Analysis
3164.72 Da
9.53
1.88
1.64
0.0607
0.45
0.65
0.23
-5.39
113.55
0.0323
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1263.25
-10.90
44.0
44.0
107.0
222.0
3.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0374461 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli (IP 76-24)
15 μg/mL
MIC
RECORD: Rec_0406991 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
RECORD: Rec_0426393 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Arthroderma simii (IP 1063-74)
30 μg/mL
MIC
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