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MYP_008970
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Basic Information
AMP-012
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
16 amino acids
C76H130N22O20
Standard
Sequence
GLFDVIRRVASVIGGL
Physicochemical Analysis
1671.98 Da
9.60
0.76
0.56
0.0476
1.21
0.76
0.33
60.60
158.12
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
681.15
-5.03
25.0
21.0
55.0
118.0
1.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0037591 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli K12
32 μg/mL
MIC
PMID31336137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31336137/
RECORD: Rec_0046167 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells [HC50 = 18.2 microg/mL]
18.2 μg/mL
HC50
PMID31336137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31336137/
RECORD: Rec_0065987 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Psedomonas aeruginosa ATCC 27853
32 μg/mL
MIC
PMID31336137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31336137/
RECORD: Rec_0072276 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Cryptococcus neoformans var. grubii H99 ATCC 2088216microg/ml)
PMID31336137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31336137/
RECORD: Rec_0079901 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 43300 MRSA
16 μg/mL
MIC
PMID31336137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31336137/
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