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MYP_008941
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Basic Information
Cytotoxic linear peptide IsCT2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C73H108N16O16
Standard
Sequence
IFGAIWNGIKSLF
Physicochemical Analysis
1465.74 Da
8.75
0.76
0.55
0.0584
1.14
0.51
0.58
-12.43
127.69
0.2308
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
517.65
-1.11
18.0
17.0
46.0
105.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0245855 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Sheep erythrocytes
50 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/14637016/ PMID14637016 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14637016/
RECORD: Rec_0253161 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
E. aerogenes
100 μg/mL
MIC
PMID28657596 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28657596/
RECORD: Rec_0253937 VERIFIED: YES
Provenance & Taxonomy
Opisthacanthus madagascariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25293
0.7 μM
MIC
PMID12054688;28657596 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12054688/
RECORD: Rec_0255556 VERIFIED: YES
Provenance & Taxonomy
Opisthacanthus madagascariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
P. aeroginosa ATCC 27853
68.3 μM
MIC
PaperPurification, structure-function analysis, and molecular characterization of novel linear peptides from scorpion Opisthacanthus madagascariensis.
RECORD: Rec_0261803 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Guinea-pig erythrocytes
50 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/14637016/ PMID14637016 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14637016/
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