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MYP_008941
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Basic Information
Cytotoxic linear peptide IsCT2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C73H108N16O16
Standard
Sequence
IFGAIWNGIKSLF
Physicochemical Analysis
1465.74 Da
8.75
0.76
0.55
0.0584
1.14
0.51
0.58
-12.43
127.69
0.2308
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
517.65
-1.11
18.0
17.0
46.0
105.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0154651 VERIFIED: YES
Provenance & Taxonomy
Opisthacanthus madagascariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli CCT 1371
3.4 μM
MIC
PMID12054688;28657596 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12054688/
RECORD: Rec_0155842 VERIFIED: YES
Provenance & Taxonomy
Opisthacanthus madagascariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
thuringensis
17.1 μM
MIC
PMID12054688;28657596 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12054688/
RECORD: Rec_0187322 VERIFIED: YES
Provenance & Taxonomy
Opisthacanthus madagascariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
6.8 μM
MIC
PMID12054688;28657596 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12054688/
RECORD: Rec_0188968 VERIFIED: YES
Provenance & Taxonomy
Opisthacanthus madagascariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
ed Gram+ Staphylococcus aureus ATCC 25293
0.7 μM
MIC
PaperPurification, structure-function analysis, and molecular characterization of novel linear peptides from scorpion Opisthacanthus madagascariensis.
RECORD: Rec_0202149 VERIFIED: YES
Provenance & Taxonomy
Opisthacanthus madagascariensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
sheep red blood cells
PMID12054688;28657596 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12054688/
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