Peptide Database

Peptide Nameκ-theraphotoxin-Pg2a (Guangxitoxin-2)

Function Ontology

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC149H230N42O47S7

DescriptionStandard

        ECRKMFGGCSVDSDCCAHLGCKPTLKYCAWDGT
    

Molecular Weight3586.13 Da

Isoelectric Point (pI)6.78

Net Charge (pH 7.0)-0.14

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0041

GRAVY Index-0.20

Hydrophobic Moment 0.29

Boman Index-0.01

Instability Index27.91

Aliphatic Index 38.48

Aromaticity 0.0909

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1420.51

LogP -16.37

H-bond Donors 56.0

H-bond Acceptors 55.0

Rotatable Bonds 115.0

Heavy Atoms 245.0

Ring Count 6.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0167243 VERIFIED: YES

Provenance & Taxonomy

OrganismChilobrachys guangxiensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide2-16; 9-21; 15-28

Bio-Activity Profile

Function

Potassium channel inhibitor Neurotoxin

Targetvoltage-gated potassium channels

MethodQualitative functional evidence