Peptide Database

Peptide Namegamma-gliadin 1380 (p111-p130; E112 and E121) ; gamma-gliadin M12 M36999 (111-130) homologous to DQ2-gamma-IV

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC108H155N29O34

DescriptionStandard

        PEQPFPQPQQEFPQPQQPQQ
    

Molecular Weight2403.56 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.04

Net Charge (pH 7.4) -2.10

Charge Density (pH 7.0) -0.1018

GRAVY Index-2.21

Hydrophobic Moment 0.40

Boman Index-0.30

Instability Index181.90

Aliphatic Index 0.00

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1011.90

LogP -11.32

H-bond Donors 26.0

H-bond Acceptors 32.0

Rotatable Bonds 70.0

Heavy Atoms 171.0

Ring Count 9.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0349978 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E112; Reported substitutions/positions: E121; Reported substitutions/positions: M12; Reported substitutions/positions: M36999

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay