Peptide Database

Peptide NameU-poneritoxin(01)-Om5b (U-PONTX(01)-Om5b) (Pilosulin-like peptide 8) (PLP8) (Poneratoxin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC278H446N66O87S4

DescriptionStandard

        MKLSALSLAFAIILMMTIMYTKADADASADAEADADAEAEAFWGALLAAAIPAITSAIQGK
    

Molecular Weight6233.17 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-5.49

Net Charge (pH 7.4) -5.72

Charge Density (pH 7.0) -0.0900

GRAVY Index0.72

Hydrophobic Moment 0.39

Boman Index0.34

Instability Index4.39

Aliphatic Index 107.87

Aromaticity 0.0656

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2397.71

LogP -19.91

H-bond Donors 82.0

H-bond Acceptors 86.0

Rotatable Bonds 205.0

Heavy Atoms 435.0

Ring Count 6.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344429 VERIFIED: YES

Provenance & Taxonomy

OrganismOdontomachus monticola [Animal]

FamilyFormicidae venom precursor-01 superfamily

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli

Activity50 μM

MethodMIC

RECORD: Rec_0392479 VERIFIED: YES