Peptide Database

Peptide NameCycloviolacin O18

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC124H191N29O38S6

DescriptionStandard

        GIPCGESCVYLPCFTAPLGCSCSSKVCY
    

Molecular Weight2888.40 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.60

Charge Density (pH 7.0) -0.0107

GRAVY Index0.72

Hydrophobic Moment 0.23

Boman Index0.30

Instability Index39.89

Aliphatic Index 66.07

Aromaticity 0.1071

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1027.58

LogP -11.57

H-bond Donors 41.0

H-bond Acceptors 44.0

Rotatable Bonds 84.0

Heavy Atoms 197.0

Ring Count 6.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188666 VERIFIED: YES

Provenance & Taxonomy

OrganismViola baoshanensis [Plant]

FamilyCyclotide

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)