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MYP_008854
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Basic Information
BPC192
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C62H111N15O12
Standard
Sequence
LKLLKFKKLQ
Physicochemical Analysis
1258.64 Da
10.48
3.76
3.55
0.3756
-0.11
0.08
-0.14
-7.39
156.00
0.1000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
472.39
-0.03
16.0
16.0
48.0
89.0
1.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0036361 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes: 49 ± 7
PaperAntimicrobial cyclic decapeptides with anticancer activity. Peptides. 2010 Nov;31(11):2017-26. doi: 10.1016/j.peptides.2010.07.027. PMID: 20708052. PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
RECORD: Rec_0053471 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: MDA-MB-231 (20 ± 0.05% Growth inhibition=40 μM)
PaperAntimicrobial cyclic decapeptides with anticancer activity. Peptides. 2010 Nov;31(11):2017-26. doi: 10.1016/j.peptides.2010.07.027. PMID: 20708052. PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
RECORD: Rec_0085905 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Xanthomonas vesicatoria 2133-2
3.1-6.2 μM
MIC
PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
RECORD: Rec_0104980 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human breast adenocarcinoma MDA-MB-231 20-30% Inhibition
40 μM
PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
RECORD: Rec_0155999 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas syringae pv. syringae EPS 94
12.5-25 μM
MIC
PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
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