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MYP_008838
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Basic Information
CEM8, MSI-78 (8-19)
Antimicrobial
Antimicrobial ▸ Antibacterial
Standard
12 amino acids
C67H113N17O13
Standard
Sequence
KAKKFGKAFVKI
Physicochemical Analysis
1364.72 Da
10.60
4.76
4.54
0.3963
-0.17
0.74
-0.08
-7.38
73.33
0.1667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
513.52
-1.77
18.0
18.0
50.0
97.0
2.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0055168 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
64-128 μg/mL
MIC
PMID25680229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25680229/
RECORD: Rec_0076473 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
512 μg/mL
MIC
PMID25680229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25680229/
RECORD: Rec_0079593 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on Pexiganan fragment [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
APD analysis reveals that this sequence is 54.55% similar to Pexiganan K: 42%, F=A: 17%. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923 or ATCC 33591 MRSA
>512 μg/mL
MIC
PaperAntimicrobial properties of membrane-active dodecapeptides derived from MSI-78.
RECORD: Rec_0098951 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on Pexiganan fragment [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
APD analysis reveals that this sequence is 54.55% similar to Pexiganan K: 42%, F=A: 17%. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial
Staphylococcus epidermidis ATCC 35984
128-256 μg/mL
MIC
PaperAntimicrobial properties of membrane-active dodecapeptides derived from MSI-78.
RECORD: Rec_0284657 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 33591
512 μg/mL
MIC
PMID25680229 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25680229/
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