Peptide Database

Peptide NameGeobacillin I (nisin analog; Bacteriocin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC136H238N40O46S8

DescriptionStandard

        VTSKSLCTPGCITGVLMCLTQNSCVSCNSCIRC
    

Molecular Weight3426.10 Da

Isoelectric Point (pI)8.27

Net Charge (pH 7.0)1.66

Net Charge (pH 7.4) 1.35

Charge Density (pH 7.0) 0.0504

GRAVY Index0.74

Hydrophobic Moment 0.33

Boman Index0.16

Instability Index45.33

Aliphatic Index 85.45

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1384.99

LogP -20.97

H-bond Donors 56.0

H-bond Acceptors 56.0

Rotatable Bonds 111.0

Heavy Atoms 230.0

Ring Count 1.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0400500 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

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