Peptide Database

Peptide NameMacromomycin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length147 amino acids

Chemical FormulaC628H1013N175O205S3

DescriptionStandard

        MSAKNKLALAARLGATAALAVGLAVSFQPSASAAAAPAVSVSPASGLSDGQQVTVTATGLTPNTVFHLGHCAFVEPGKYGCDKTTAKDVVSDAQGKVNTTIVVHSSFDAVVTADGAVWGKVDAKTTSTQVGLGSASGEGGGQAVTFK
    

Molecular Weight14391.01 Da

Isoelectric Point (pI)7.80

Net Charge (pH 7.0)0.75

Net Charge (pH 7.4) 0.33

Charge Density (pH 7.0) 0.0051

GRAVY Index0.24

Hydrophobic Moment 0.43

Boman Index0.20

Instability Index15.74

Aliphatic Index 81.70

Aromaticity 0.0476

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5996.29

LogP -81.42

H-bond Donors 209.0

H-bond Acceptors 212.0

Rotatable Bonds 465.0

Heavy Atoms 1011.0

Ring Count 16.0

Amide Bonds 155.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0027036 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptomyces sp. CB02130 [Bacterium]

FamilyNeocarzinostatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal