Peptide Database

Peptide NameSLAY-screened peptide P4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC39H62N14O13S

DescriptionStandard

        AGAAFNSCAR
    

Molecular Weight967.06 Da

Isoelectric Point (pI)8.29

Net Charge (pH 7.0)0.79

Net Charge (pH 7.4) 0.58

Charge Density (pH 7.0) 0.0786

GRAVY Index0.33

Hydrophobic Moment 0.48

Boman Index0.10

Instability Index33.11

Aliphatic Index 40.00

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 450.44

LogP -7.22

H-bond Donors 17.0

H-bond Acceptors 15.0

Rotatable Bonds 29.0

Heavy Atoms 67.0

Ring Count 1.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0178588 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/