Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC119H189N39O33S

DescriptionStandard

        HSHRDFQPVLHLVALNSPLSGGMRG
    

Molecular Weight2726.08 Da

Isoelectric Point (pI)9.62

Net Charge (pH 7.0)1.02

Net Charge (pH 7.4) 0.67

Charge Density (pH 7.0) 0.0409

GRAVY Index-0.23

Hydrophobic Moment 0.59

Boman Index0.05

Instability Index38.09

Aliphatic Index 89.60

Aromaticity 0.0400

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1138.15

LogP -12.53

H-bond Donors 39.0

H-bond Acceptors 38.0

Rotatable Bonds 86.0

Heavy Atoms 192.0

Ring Count 6.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0363678 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyEndostatin-derived peptide

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Anticancer Anti-angiogenic Cytotoxic

TargetBxPC-3

Activity7 mg/kg/d

MethodInhibition

RECORD: Rec_0374191 VERIFIED: YES