Peptide Database

Peptide NameBrevinin-1Pb

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC368H587N91O105S4

DescriptionStandard

        MFTLNKFLLLLFFLGTINLSLCEEERNAEEERRDEPDETDVEVEKRFLPIIAGIAAKVFPKIFCAISKKC
    

Molecular Weight8094.40 Da

Isoelectric Point (pI)4.90

Net Charge (pH 7.0)-3.50

Net Charge (pH 7.4) -3.79

Charge Density (pH 7.0) -0.0501

GRAVY Index0.07

Hydrophobic Moment 0.61

Boman Index0.05

Instability Index48.80

Aliphatic Index 103.14

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3163.89

LogP -20.72

H-bond Donors 110.0

H-bond Acceptors 106.0

Rotatable Bonds 276.0

Heavy Atoms 568.0

Ring Count 10.0

Amide Bonds 72.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0050838 VERIFIED: NO

Provenance & Taxonomy

OrganismLithobates pipiens [Animal]

FamilyBrevinin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0419275 VERIFIED: YES