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MYP_008775
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Basic Information
PenShufLeu
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
16 amino acids
C105H170N34O20
Standard
Sequence
RWFKIQLQIRRWKNKK
Physicochemical Analysis
2228.69 Da
12.00
6.76
6.55
0.4223
-1.61
0.54
-0.59
137.25
73.12
0.1875
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
950.45
-4.79
35.0
27.0
79.0
159.0
5.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0175797 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 25.0%, E 0.0%, T 6.2%, C 68.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0224460 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells
65± 2.5 μM
HC50
PMID23085001 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23085001/
RECORD: Rec_0270622 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
32 μM
MIC
PMID23085001 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23085001/
RECORD: Rec_0293791 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus(ATCC 33591)
16 μM
MIC
PaperPubMed PMID: 23085001 PMID23085001 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23085001/
RECORD: Rec_0294185 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperPubMed PMID: 23085001 PMID23085001 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23085001/
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