Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC444H722N130O130S8

DescriptionStandard

        MRTLIILAAILLVALQAQAGLLQARADEAAAAEKKISADNNDVAISFAWDESLIPRNSGSRENMACFCRIPSCIAGERRLGTCLYQGRLWAFCC
    

Molecular Weight10217.80 Da

Isoelectric Point (pI)7.56

Net Charge (pH 7.0)0.46

Net Charge (pH 7.4) 0.14

Charge Density (pH 7.0) 0.0049

GRAVY Index0.28

Hydrophobic Moment 0.52

Boman Index0.09

Instability Index40.27

Aliphatic Index 103.09

Aromaticity 0.0638

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4193.35

LogP -41.74

H-bond Donors 153.0

H-bond Acceptors 139.0

Rotatable Bonds 340.0

Heavy Atoms 712.0

Ring Count 10.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0198375 VERIFIED: NO

Provenance & Taxonomy

OrganismCebus imitator [Animal]

FamilyDefensin

Tax ID9516

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence