Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC530H870N134O155S4

DescriptionStandard

        MKNSNLFKIASVTSIVSLFAIATFLMGSSEGIASLASIDFNSGNQFALDLATNLGISRKTAYAAIGVIMTTGDVLTILSLLAVVLGGTGLVTAAMVATAKKLATKHGKKYAAEW
    

Molecular Weight11727.64 Da

Isoelectric Point (pI)9.63

Net Charge (pH 7.0)3.59

Net Charge (pH 7.4) 3.30

Charge Density (pH 7.0) 0.0315

GRAVY Index0.70

Hydrophobic Moment 0.52

Boman Index0.31

Instability Index6.95

Aliphatic Index 114.82

Aromaticity 0.0702

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4596.71

LogP -45.83

H-bond Donors 163.0

H-bond Acceptors 164.0

Rotatable Bonds 394.0

Heavy Atoms 823.0

Ring Count 10.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0179206 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus altitudinis [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal