Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC245H414N70O82S7

DescriptionStandard

        MSTKDFNLDLVSVSKKDSGASPRITSISLCTPGCKTGALMGCSLSTATCHCSIHVSK
    

Molecular Weight5876.78 Da

Isoelectric Point (pI)8.74

Net Charge (pH 7.0)2.62

Net Charge (pH 7.4) 2.22

Charge Density (pH 7.0) 0.0460

GRAVY Index0.13

Hydrophobic Moment 0.31

Boman Index0.07

Instability Index35.11

Aliphatic Index 75.26

Aromaticity 0.0175

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2423.60

LogP -34.78

H-bond Donors 92.0

H-bond Acceptors 94.0

Rotatable Bonds 196.0

Heavy Atoms 404.0

Ring Count 5.0

Amide Bonds 57.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0144289 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus lactis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0295903 VERIFIED: NO