Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length177 amino acids

Chemical FormulaC858H1365N259O245S11

DescriptionStandard

        MNAKIRYGLSAAVLALIGAGASAPEILDQFLDEKEGNHTMAYRDGAGIWTICRGATRVDGKPVIPGMKLSKGKCDRVNAIERDKALAWVEKNIRVPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRINAGDRRGACEAIRWWIKDGGRDCRIRSNNCYGQVFRRDQESALACWGIDR
    

Molecular Weight19581.32 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)9.53

Net Charge (pH 7.4) 9.10

Charge Density (pH 7.0) 0.0538

GRAVY Index-0.39

Hydrophobic Moment 0.73

Boman Index-0.07

Instability Index40.35

Aliphatic Index 75.65

Aromaticity 0.0847

Extinction Coeff. Reduced 34950.00

Extinction Coeff. Oxidized 35450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8156.46

LogP -86.26

H-bond Donors 295.0

H-bond Acceptors 267.0

Rotatable Bonds 651.0

Heavy Atoms 1373.0

Ring Count 29.0

Amide Bonds 188.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028031 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyLysozyme

Tax ID585034

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence