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MYP_008681
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Basic Information
Violacin A
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
27 amino acids
C129H199N33O38S6
Standard
Sequence
SAISCGETCFKFKCYTPRCSCSYPVCK
Physicochemical Analysis
3012.55 Da
8.64
2.40
2.09
0.0888
0.02
0.39
-0.01
25.62
28.89
0.1481
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1141.44
-13.42
47.0
47.0
93.0
206.0
6.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0301337 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
Defensin
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial
show insecticidal
PaperPubMed PMID: 16872274 | PubMed PMID: 16488428 PMID16872274;16488428 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16872274/
RECORD: Rec_0353922 VERIFIED: NO
Provenance & Taxonomy
Viola odorata [Plant]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
5-19; 9-21; 14-26
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0358290 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Uterotonic Insecticidal Antiviral Anti-HIV Antimicrobial manual_review_only Cytotoxic Hemolytic
Human erythrocytes
1.5 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/16488428/ PMID16488428 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16488428/
RECORD: Rec_0373234 VERIFIED: YES
Provenance & Taxonomy
Viola odorata [Plant]
Cyclotide
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID16488428 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16488428/
RECORD: Rec_0390228 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide; DSSP H 0.0%, E 33.3%, T 37.0%, C 29.6% [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Toxic Antimicrobial Hemolytic Cytotoxic Uterotonic Insecticidal manual_review_only
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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