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MYP_008660
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Basic Information
Brevinin-2HSb
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
33 amino acids
C142H251N41O46S3
Standard
Sequence
GLLDTLKNMAINAAKGAGQSVLNTLSCKLSKTC
Physicochemical Analysis
3364.95 Da
9.31
2.74
2.50
0.0830
0.21
0.44
0.10
19.21
103.64
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1429.64
-18.52
51.0
52.0
118.0
232.0
0.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0296232 VERIFIED: NO
Provenance & Taxonomy
Rana hosii,Odorrana hosii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus, Escherichia coli
RECORD: Rec_0331412 VERIFIED: YES
Provenance & Taxonomy
Rana hosii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
PMID18621071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18621071/
RECORD: Rec_0370320 VERIFIED: YES
Provenance & Taxonomy
Odorrana hosii [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
27-33
Bio-Activity Profile
Antimicrobial Antibacterial
PaperJ.M. Conlon et al. / Toxicon 52 (2008) 465-473. Characterization of antimicrobial peptides from the skin secretions of the Malaysian frogs, Odorrana hosii and Hylarana picturata (Anura:Ranidae) PMID18621071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18621071/
RECORD: Rec_0381285 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0410721 VERIFIED: YES
Provenance & Taxonomy
Rana hosii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25726
PMID18621071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18621071/
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