Peptide Database

Peptide NameDefensin_propep domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC343H554N104O115S3

DescriptionStandard

        MRTLAILAAILLVALQAQAESLQERADEAATQEQPGEDDQDLAVSFEENGLSTPRASGRQARFSQHCAMGRITW
    

Molecular Weight8070.89 Da

Isoelectric Point (pI)4.57

Net Charge (pH 7.0)-5.40

Net Charge (pH 7.4) -5.69

Charge Density (pH 7.0) -0.0730

GRAVY Index-0.34

Hydrophobic Moment 0.59

Boman Index-0.04

Instability Index42.43

Aliphatic Index 83.38

Aromaticity 0.0405

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3566.09

LogP -41.97

H-bond Donors 123.0

H-bond Acceptors 114.0

Rotatable Bonds 272.0

Heavy Atoms 565.0

Ring Count 7.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0336217 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic