Peptide Database

Peptide NameP9

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC152H231N33O47S

DescriptionStandard

        SALEEQYKTFLDKFMHELEDLLYQLSL
    

Molecular Weight3304.72 Da

Isoelectric Point (pI)4.35

Net Charge (pH 7.0)-4.44

Net Charge (pH 7.4) -4.71

Charge Density (pH 7.0) -0.1646

GRAVY Index-0.30

Hydrophobic Moment 0.63

Boman Index0.05

Instability Index55.82

Aliphatic Index 104.81

Aromaticity 0.1481

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1311.77

LogP -6.99

H-bond Donors 44.0

H-bond Acceptors 45.0

Rotatable Bonds 113.0

Heavy Atoms 233.0

Ring Count 5.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346536 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anti-SARS-CoV-2

Targetinhibition of replication in Calu-3 cells

Activity0.053 μM

MethodIC50

RECORD: Rec_0377171 VERIFIED: YES