Peptide Database

Peptide Namealpha-Conotoxin Lp1.9

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC63H97N21O30S5

DescriptionStandard

        SCCSDSDCNANHPDMCS
    

Molecular Weight1788.89 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.49

Net Charge (pH 7.4) -3.81

Charge Density (pH 7.0) -0.2052

GRAVY Index-0.69

Hydrophobic Moment 0.14

Boman Index-0.17

Instability Index33.79

Aliphatic Index 5.88

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 827.81

LogP -15.74

H-bond Donors 31.0

H-bond Acceptors 33.0

Rotatable Bonds 55.0

Heavy Atoms 119.0

Ring Count 2.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0173498 VERIFIED: NO

Provenance & Taxonomy

OrganismConus leopardus [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-8; 3-16

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0176279 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 11.8%, T 52.9%, C 35.3% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic