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MYP_008522
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Basic Information
Big gastrin
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Standard
34 amino acids
C175H262N44O51S
Standard
Sequence
QLGLQGSPHLVADLSKKQGPWLEKEEAAYGWMDF
Physicochemical Analysis
3830.28 Da
4.90
-2.15
-2.41
-0.0631
-0.56
0.39
0.07
54.92
74.71
0.1176
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1520.82
-11.05
50.0
51.0
125.0
271.0
9.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0090244 VERIFIED: YES
Provenance & Taxonomy
Equus caballus [Animal]
Big gastrin
9796
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
Amidation
18:Pyrrolidone carboxylic acid
Bio-Activity Profile
Hormone Endocrine Myotropic Receptor modulation
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Big gastrin (Equus caballus): PMID 9716385 PMID9716385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9716385/
RECORD: Rec_0246963 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0421740 VERIFIED: YES
Provenance & Taxonomy
Equus caballus [Animal]
Gastrin/cholecystokinin
9796
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamate
Amidation
Gln18 Pyroglutamylation
Bio-Activity Profile
Hormone Gastrointestinal Neuropeptide
PMID9716385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9716385/