Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC540H874N148O163S4

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLMIGNASLTIDMNWNIRTWMFKGSGRGTVHISKVFVTAIFSTPVDNTGPTSISLTSCRTTSGDIDIKLNGKT
    

Molecular Weight12175.87 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)4.21

Net Charge (pH 7.4) 3.97

Charge Density (pH 7.0) 0.0370

GRAVY Index0.04

Hydrophobic Moment 0.54

Boman Index0.13

Instability Index17.27

Aliphatic Index 93.16

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4958.77

LogP -56.66

H-bond Donors 177.0

H-bond Acceptors 174.0

Rotatable Bonds 402.0

Heavy Atoms 855.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0333056 VERIFIED: NO

Provenance & Taxonomy

OrganismBombycilla garrulus (Bohemian waxwing) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria