‹ ›
MYP_008509
← PREVIOUS NEXT → BACK
Basic Information
Amp1L, Amp1EP
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C90H173N21O16
Standard
Sequence
LKLLKKLLKKLLKLL
Physicochemical Analysis
1805.47 Da
10.70
5.75
5.54
0.3836
0.72
0.81
0.04
-35.95
234.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
626.84
2.37
22.0
22.0
71.0
127.0
0.0
14.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0038645 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Amp1L [Pseudomonas aeruginosa
6.25-12.5 μM
MIC
PMID34043312 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34043312/
RECORD: Rec_0056392 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Amp1EP [(Isopeptide formation: K5, K9, and K13) - Pseudomonas aeruginosa
12.5 μM
MIC
PMID34043312 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34043312/
RECORD: Rec_0085689 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Amp1EP [(Isopeptide formation: K5, K9, and K13) - Pseudomonas aeruginosa
6.25 μM
MIC
PMID34043312 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34043312/
RECORD: Rec_0093052 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Host DefenseÐLike Lytic Peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Anticancer
CL-1
3 μM
LC50
PMID16707464 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16707464/
RECORD: Rec_0101380 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID35759644 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35759644/
1 2 3 ... 5 NEXT LAST
Showing 5 records on this page · Page 1 of 5