MYP_008464
Potassium channel toxin alpha-KTx 9.4
Annotation / Sequence feature
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Nuclear export signal
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Immunology
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Innate immune defense
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Host defense peptide
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Host defense activity
Membrane / Ion-channel modulation
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Ion channel inhibition
Membrane / Ion-channel modulation
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Potassium channel modulation
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Potassium channel inhibitor
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
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Toxic
Venom / Toxin
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General toxin
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Toxin
Venom / Toxin
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Toxin
Standard
32 amino acids
C139H236N42O44S8
Standard
VGCAECPMHCKGKMAKPTCENEVCKCNIGKKD
3456.14 Da
8.30
1.77
1.40
0.0553
-0.54
0.29
-0.15
59.79
36.56
0.0000
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1388.25
-16.24
51.0
55.0
119.0
233.0
3.0
33.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0008594
VERIFIED: YES
Provenance & Taxonomy
Mesobuthus tamulus [Animal]
Potassium channel inhibitor family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-19; 6-24; 10-26
Bio-Activity Profile
Toxin
Venom
Potassium channel inhibitor family
Ion channel inhibitor
Pathogenesis-associated
Host defense
RECORD: Rec_0232265
VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic
Cytotoxic
RECORD: Rec_0351832
VERIFIED: NO
Provenance & Taxonomy
Buthus tamulus,Mesobuthus tamulus [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-19; 6-24; 10-26
Bio-Activity Profile
Toxin
potassium channel Kv1.1, Kv1