MYP_008460
R-DIM-P-LF11-322
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
▸
Cytotoxic
Antimicrobial
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
▸
General toxin
▸
Cytotoxic
Standard
19 amino acids
C127H201N45O20
Standard
PFWRIRIRRPRRIRIRWFP
2678.24 Da
12.00
7.96
7.90
0.4189
-1.00
0.57
-0.55
126.36
82.11
0.2105
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1082.33
-4.21
44.0
28.0
83.0
192.0
9.0
18.0
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
RECORD: Rec_0165984
VERIFIED: YES
Provenance & Taxonomy
Human lactoferricin [Animal]
Lactoferricin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Anticancer
A-375
23.3±1.7 μM
LC50
RECORD: Rec_0201677
VERIFIED: YES
Provenance & Taxonomy
Human lactoferricin [Animal]
Lactoferricin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Anticancer
SBcl-2
10.4±0.7 μM
LC50
RECORD: Rec_0319825
VERIFIED: YES
Provenance & Taxonomy
Human lactoferricin [Animal]
Lactoferricin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic
Normal Human Dermal Fibroblasts (NHDF)
101 μM
LC50
RECORD: Rec_0424154
VERIFIED: YES
Provenance & Taxonomy
Human lactoferricin [Animal]
Lactoferricin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic