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MYP_008458
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Basic Information
Esculentin-2CHa (7-37)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
31 amino acids
C141H247N41O39S2
Standard
Sequence
RGVAKFASKGLGKDLAKLGVDLVACKISKQC
Physicochemical Analysis
3204.85 Da
9.79
4.74
4.49
0.1528
0.18
0.67
0.02
10.50
103.87
0.0323
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1312.49
-12.91
48.0
46.0
115.0
223.0
1.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0078979 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human lung carcinoma A549
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0084135 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii NM35
200 μM
MIC
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0128148 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
A549
>100 μM
LC50
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0153748 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0193448 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
>200 μM
Hemolysis
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
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