Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC449H693N127O133S14

DescriptionStandard

        MKLTRFFLAAVVIAACFCFLQTDASPFTQEVQHEDEMNSEAPQMNYHSTETTPEQSNPLALFRSKRQSHLSMCRYCCKCCRNKGCGFCCKF
    

Molecular Weight10446.99 Da

Isoelectric Point (pI)8.06

Net Charge (pH 7.0)1.67

Net Charge (pH 7.4) 1.14

Charge Density (pH 7.0) 0.0184

GRAVY Index-0.29

Hydrophobic Moment 0.68

Boman Index-0.06

Instability Index63.63

Aliphatic Index 47.25

Aromaticity 0.1099

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4205.55

LogP -46.78

H-bond Donors 154.0

H-bond Acceptors 152.0

Rotatable Bonds 343.0

Heavy Atoms 723.0

Ring Count 17.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0053265 VERIFIED: NO

Provenance & Taxonomy

OrganismMisgurnus anguillicaudatus [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal