Peptide Database

Peptide NameKappa-scoloptoxin

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel modulation

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC150H223N43O39S6

DescriptionStandard

        AQNHYCKEHNCPPGKHCPKVPIACVYGPCCF
    

Molecular Weight3445.03 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)2.00

Net Charge (pH 7.4) 1.56

Charge Density (pH 7.0) 0.0644

GRAVY Index-0.40

Hydrophobic Moment 0.35

Boman Index0.03

Instability Index51.64

Aliphatic Index 37.74

Aromaticity 0.0968

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1263.50

LogP -11.98

H-bond Donors 45.0

H-bond Acceptors 50.0

Rotatable Bonds 100.0

Heavy Atoms 238.0

Ring Count 11.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0304308 VERIFIED: YES

Provenance & Taxonomy

OrganismScolopendra subspinipes [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin Channel blocker Ion channel blocker Potassium channel blocker

Targetvoltage-gated potassium channel currents, potassium channel currents

Activity0.57 μM

MethodIC50