Peptide Database

Peptide Name[D-Trp8] CLA

Function Ontology

Antimicrobial

Antiparasitic ▸ Antimalarial

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC59H88N10O10

DescriptionStandard

        LIILVPPWF
    

Molecular Weight1097.39 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0267

GRAVY Index2.17

Hydrophobic Moment 0.25

Boman Index0.91

Instability Index69.89

Aliphatic Index 205.56

Aromaticity 0.2222

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 294.33

LogP 4.10

H-bond Donors 9.0

H-bond Acceptors 10.0

Rotatable Bonds 28.0

Heavy Atoms 79.0

Ring Count 5.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161249 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyCyclic peptide

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Antimalarial

TargetPlasmodium falciparum clone FCH5.C2

Activity1.1 μg/mL

MethodIC50; PLDH assay